Curevac AG

U.S. Patent No. 11,149,278


This prior art search report presents the mappings of the various elements of claim of 1 of U.S. Patent No. 11,149,278 (‘278 patent), titled “Artificial nucleic acid molecules for improved protein expression”, filed by CureVac AG on December 11, 2015, following the patent’s subsequent publication on October 19, 2021.

The patent claims an artificial nucleic acid molecule comprising an open reading frame and a 3′-UTR comprising at least one poly(A) sequence or a polyadenylation signal, a vector comprising the artificial nucleic acid molecule, a cell comprising the artificial nucleic acid molecule or the vector, a pharmaceutical composition comprising the artificial nucleic acid molecule or the vector, and a kit comprising the artificial nucleic acid molecule, the vector and/or the pharmaceutical composition. Moreover, the invention concerns the use of the artificial nucleic acid molecule, the vector, the kit, or the pharmaceutical composition as a medicament, as a vaccine or in gene therapy.

This preliminary search report includes the following:

  • References found from the preliminary search
  • Claims mapping chart
  • Copies of the selected references with highlighted excerpts
  • Search strategies used in conducting the prior art search


This ParolaPRIME™ report is not legal advice. The suggested correspondences between the features disclosed in the patent-at-issue and those disclosed in each reference reflect what Parola Analytics believes are technical similarities between those respective sets of features. Parola Analytics makes no representation concerning any legal status or effect that may arise from documents mentioned in this report, such as the validity of any apparent priority date or the assertability of any document as prior art against a patent. You should independently obtain legal counsel before attempting to rely on any portion of this report in a legal proceeding.

The references presented in this report are only preliminary and do not represent results from an exhaustive search. For the full report, request a quote.

Questions? Read our Terms and Conditions, FAQs or contact us.

Related Reports

Customer Care

Subscribe to our newsletter

  • Questions? Check our privacy policy.
  • This field is for validation purposes and should be left unchanged.

Patent and IP updates straight to your inbox

Sign up now to receive monthly patent news, analysis and free insight reports.

We don’t spam, we promise.

Request a Quote

  • Hidden
  • Hidden
  • This field is for validation purposes and should be left unchanged.


1. Parola Analytics and Avontis are distinct entities and operate independently. Any references to Avontis or its services do not constitute a legal partnership. 

2. Parola Analytics does not provide legal services. Our services are limited to research and technical analysis. Any information provided by Parola Analytics should not be construed as legal advice.